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mouse tac2 cre strain background c57bl 6j  (Jackson Laboratory)

 
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    Structured Review

    Jackson Laboratory mouse tac2 cre strain background c57bl 6j
    (A) Ileums from 3-week-old <t>Tac2</t> knockout (KO) and wild-type (WT) littermates immunostained as in . Scale bar, 50 μm. (B) Number of S100B + glia in each spatial-morphological class of the ileum in Tac2 KO (orange) and WT (gray) mice ( n = 4–5 mice/genotype). (C) Number of ANNA-1 + neurons in each enteric plexus in Tac2 KO and WT mice. (D) Whole-mount preparation from adult Tac2 Cre/+ Rosa26 tdTomato/+ mouse ileum immunolabeled with S100B (green). Scale bar, 100 μm. Graph shows percentage of tdTomato + neurons in the myenteric plexus. (E) Whole-mount preparation of Tac2 Cre/+ Rosa26 tdTomato/+ ileum immunostained for CALB2 (green) and shown at the same scale as (A). (F) Association of TAC3 SNPs with hard stool (top) and human esophagus muscularis eQTLs (bottom) from UK Biobank and GTEx Portal data, respectively. Genomic region analyzed is shown and arrow depicts the direction of TAC3 transcription. For (B) and (C), two-way ANOVA with Šidák’s multiple comparisons test was used (* p < 0.05 and **** p < 0.0001). See also .
    Mouse Tac2 Cre Strain Background C57bl 6j, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+tac2+cre+strain+background+c57bl+6j/background+strain/pmc12832054-65-0-7
    Average 86 stars, based on 1 article reviews
    mouse tac2 cre strain background c57bl 6j - by Bioz Stars, 2026-09
    86/100 stars

    Images

    1) Product Images from "Tachykinin signaling defines distinct populations of glia in the enteric nervous system"

    Article Title: Tachykinin signaling defines distinct populations of glia in the enteric nervous system

    Journal: Neuron

    doi: 10.1016/j.neuron.2025.11.030

    (A) Ileums from 3-week-old Tac2 knockout (KO) and wild-type (WT) littermates immunostained as in . Scale bar, 50 μm. (B) Number of S100B + glia in each spatial-morphological class of the ileum in Tac2 KO (orange) and WT (gray) mice ( n = 4–5 mice/genotype). (C) Number of ANNA-1 + neurons in each enteric plexus in Tac2 KO and WT mice. (D) Whole-mount preparation from adult Tac2 Cre/+ Rosa26 tdTomato/+ mouse ileum immunolabeled with S100B (green). Scale bar, 100 μm. Graph shows percentage of tdTomato + neurons in the myenteric plexus. (E) Whole-mount preparation of Tac2 Cre/+ Rosa26 tdTomato/+ ileum immunostained for CALB2 (green) and shown at the same scale as (A). (F) Association of TAC3 SNPs with hard stool (top) and human esophagus muscularis eQTLs (bottom) from UK Biobank and GTEx Portal data, respectively. Genomic region analyzed is shown and arrow depicts the direction of TAC3 transcription. For (B) and (C), two-way ANOVA with Šidák’s multiple comparisons test was used (* p < 0.05 and **** p < 0.0001). See also .
    Figure Legend Snippet: (A) Ileums from 3-week-old Tac2 knockout (KO) and wild-type (WT) littermates immunostained as in . Scale bar, 50 μm. (B) Number of S100B + glia in each spatial-morphological class of the ileum in Tac2 KO (orange) and WT (gray) mice ( n = 4–5 mice/genotype). (C) Number of ANNA-1 + neurons in each enteric plexus in Tac2 KO and WT mice. (D) Whole-mount preparation from adult Tac2 Cre/+ Rosa26 tdTomato/+ mouse ileum immunolabeled with S100B (green). Scale bar, 100 μm. Graph shows percentage of tdTomato + neurons in the myenteric plexus. (E) Whole-mount preparation of Tac2 Cre/+ Rosa26 tdTomato/+ ileum immunostained for CALB2 (green) and shown at the same scale as (A). (F) Association of TAC3 SNPs with hard stool (top) and human esophagus muscularis eQTLs (bottom) from UK Biobank and GTEx Portal data, respectively. Genomic region analyzed is shown and arrow depicts the direction of TAC3 transcription. For (B) and (C), two-way ANOVA with Šidák’s multiple comparisons test was used (* p < 0.05 and **** p < 0.0001). See also .

    Techniques Used: Knock-Out, Immunolabeling



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    mouse tac2 cre strain background c57bl 6j  (Jackson Laboratory)
    86
    Jackson Laboratory mouse tac2 cre strain background c57bl 6j
    (A) Ileums from 3-week-old <t>Tac2</t> knockout (KO) and wild-type (WT) littermates immunostained as in . Scale bar, 50 μm. (B) Number of S100B + glia in each spatial-morphological class of the ileum in Tac2 KO (orange) and WT (gray) mice ( n = 4–5 mice/genotype). (C) Number of ANNA-1 + neurons in each enteric plexus in Tac2 KO and WT mice. (D) Whole-mount preparation from adult Tac2 Cre/+ Rosa26 tdTomato/+ mouse ileum immunolabeled with S100B (green). Scale bar, 100 μm. Graph shows percentage of tdTomato + neurons in the myenteric plexus. (E) Whole-mount preparation of Tac2 Cre/+ Rosa26 tdTomato/+ ileum immunostained for CALB2 (green) and shown at the same scale as (A). (F) Association of TAC3 SNPs with hard stool (top) and human esophagus muscularis eQTLs (bottom) from UK Biobank and GTEx Portal data, respectively. Genomic region analyzed is shown and arrow depicts the direction of TAC3 transcription. For (B) and (C), two-way ANOVA with Šidák’s multiple comparisons test was used (* p < 0.05 and **** p < 0.0001). See also .
    Mouse Tac2 Cre Strain Background C57bl 6j, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+tac2+cre+strain+background+c57bl+6j/background+strain/pmc12832054-65-0-7
    Average 86 stars, based on 1 article reviews
    mouse tac2 cre strain background c57bl 6j - by Bioz Stars, 2026-09
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    (A) Ileums from 3-week-old Tac2 knockout (KO) and wild-type (WT) littermates immunostained as in . Scale bar, 50 μm. (B) Number of S100B + glia in each spatial-morphological class of the ileum in Tac2 KO (orange) and WT (gray) mice ( n = 4–5 mice/genotype). (C) Number of ANNA-1 + neurons in each enteric plexus in Tac2 KO and WT mice. (D) Whole-mount preparation from adult Tac2 Cre/+ Rosa26 tdTomato/+ mouse ileum immunolabeled with S100B (green). Scale bar, 100 μm. Graph shows percentage of tdTomato + neurons in the myenteric plexus. (E) Whole-mount preparation of Tac2 Cre/+ Rosa26 tdTomato/+ ileum immunostained for CALB2 (green) and shown at the same scale as (A). (F) Association of TAC3 SNPs with hard stool (top) and human esophagus muscularis eQTLs (bottom) from UK Biobank and GTEx Portal data, respectively. Genomic region analyzed is shown and arrow depicts the direction of TAC3 transcription. For (B) and (C), two-way ANOVA with Šidák’s multiple comparisons test was used (* p < 0.05 and **** p < 0.0001). See also .

    Journal: Neuron

    Article Title: Tachykinin signaling defines distinct populations of glia in the enteric nervous system

    doi: 10.1016/j.neuron.2025.11.030

    Figure Lengend Snippet: (A) Ileums from 3-week-old Tac2 knockout (KO) and wild-type (WT) littermates immunostained as in . Scale bar, 50 μm. (B) Number of S100B + glia in each spatial-morphological class of the ileum in Tac2 KO (orange) and WT (gray) mice ( n = 4–5 mice/genotype). (C) Number of ANNA-1 + neurons in each enteric plexus in Tac2 KO and WT mice. (D) Whole-mount preparation from adult Tac2 Cre/+ Rosa26 tdTomato/+ mouse ileum immunolabeled with S100B (green). Scale bar, 100 μm. Graph shows percentage of tdTomato + neurons in the myenteric plexus. (E) Whole-mount preparation of Tac2 Cre/+ Rosa26 tdTomato/+ ileum immunostained for CALB2 (green) and shown at the same scale as (A). (F) Association of TAC3 SNPs with hard stool (top) and human esophagus muscularis eQTLs (bottom) from UK Biobank and GTEx Portal data, respectively. Genomic region analyzed is shown and arrow depicts the direction of TAC3 transcription. For (B) and (C), two-way ANOVA with Šidák’s multiple comparisons test was used (* p < 0.05 and **** p < 0.0001). See also .

    Article Snippet: Mouse: Tac2 Cre/+ Strain Background: C57BL/6J , The Jackson Laboratory , RRID: IMSR_JAX:018938.

    Techniques: Knock-Out, Immunolabeling